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Join us for an exciting exploration From Molecular Mechanisms to Therapeutic Opportunities: KLF/SP Factors and Downstream Signalling Effectors at the International Meeting of the Krüppel-like Factor Society.

The sessions focus on the latest advances in KLF/SP transcription factor biology, from fundamental signaling pathways to translational breakthroughs.

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Full Registration (All inclusive, no hotel) 500,00 € / 57 available 2-Day Pass (All inclusive, no hotel) 250,00 € / 77 available

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Hotel Friday 90,00 € Hotel Saturday 90,00 € Hotel Sunday 90,00 €

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Info

Day 1 FRIDAY, 13th November 2026

14:30-15:00 Arrival & reception Early Career

15:00 – 16:15 Early Career Investigators – Session A 5x 15 min

Chairs: Shaohan Wang, Justus-Liebig-Universität Gießen, Germany

16:15 –16:30 Coffee break

16:30– 17:30 Early Career Investigators – Session B 5x 15 min

Laura Priesmeier, Medical University Center Goettingen, Germany

Thomas Koertl, Justus-Liebig-Universität Gießen, Germany

17:30 –18:30 Coffee break and poster sessions

Poster Jury: Eric Schoger, Heidelberg University, Germany; Giulia Germana, University Hospital Zurich, Swiss

18:45– 19:00 Opening Session

Chairs: Laura Zelarayán, Justus-Liebig-Universität Gießen, Germany; Chen Ceshi, Kunming Medical University, China

19:00– 20:00 Keynote Lecture: Pioneer Roles of Krüppel-Like Factors: Chromatin Rewiring in Development, Physiology, and Disease

Raul Urrutia, Medical College of Wisconsin, USA

20:00 Opening Dinner

Day 2 SATURDAY, 14th November 2026

08:30–09:00 Registration & coffee

09:00–10:40 – Session 1: Regeneration and Pluripotency

Chairs: TBA

09:00-9:25 To have (not to have) KLFs - the gut road to the regeneration, Agnieszka Bialkowska, Stony Brook University, USA

09:25-9:50 Structure-based engineering of the pioneer factor KLF4 enables new routes for pluripotency induction, Ralf Jauch, Hong Kong, China

9:50-10:15 Induction of adult cardiomyocyte renewal by modulating KLF1 pathways, Kazu Kikuchi, National Cerebral and Cardiovascular Center, Japan

10:15:10:40 Topic TBA, Sven Reischauer, Justus-Liebig-Universität Gießen, Germany

10:40 –11:00 Coffee break

11:00-12:40 – Session 2: Blood and Immune cells

Chairs: TBA

11:00-11:25 Talk from Kate Quinlan, UNSW Sydney, Australia

11:25-11:50 Talk from Merlin Crossley, UNSW Sydney, Australia

11:50-12:15 Talk from James Bieker, Mount Sinai School of Medicine, USA

12:15-12:40 Talk from Jan Frayne, University of Bristol, UK

12:40 –14:00 Group photo and Lunch break

14:00 –15:40 – Session 3: Immune cells crosstalk

Chairs: TBA

14:00 - 14:25 Role of KLF15 in exosome in heart failure development, Giulia Germena, University of Zürich, Swiss

14:25 - 14:50 Innate immune memory in heart failure, Ichiro Manabe, Chiba University, Japan

14:50 - 15:15 KLF4: A Molecular Switch in Immune Cell Identity and Function, Daniel Lacorazza, Baylor College of Medicine, USA

14:50 - 15:40 TBA

15:40 –16:00 Coffee break

16:00-17:00 Translational Session

Chairs: TBA

16:00-16:30 Making Science for patients, Samuel Sossalla, Kerckhoff Heart Research Institute in association with Justus Liebig, University Giessen, University Hospital Giessen and Marburg

16:30-17:00 Translational Applications of Partial Cellular Reprogramming: From Genetics to mRNA-Based Interventions, Johnny Kim, TRON – Translational Oncology at the University Medical Centre of Johannes Gutenberg University Mainz

17:00 – 17:15 Coffee break

19:00 Dinner

Seitenumbruch

Day 3 SUNDAY 15th, November 2026

08:30–10:10 – Session 4: Cardiac diseases

Chairs: TBA

08:30 - 8:55 Talk from Mario Pavez-Giani, Justus-Liebig-Universität Gießen, Germany

8:55 - 9:20 Cardiomyocyte KLF5: A Master Switch Driving the Expanding Landscape of Cardiotoxicity, Konstantinos Drosatos, University of Cincinnati College of Medicine, USA

09:20 -9:45 Linking PTMs and KLF/SP regulation in the heart, Adam Wende, University of Alabama at Birmingham, USA

9:45 -10:10 Talk from Shirin Doroudgar, The University of Arizona, USA

10:10 - 10:30 Coffee break

10:30–12:10 – Session 5: Bone and muscle cells

Chairs: TBA

10:30 - 10:55 Disruption of KLF expression in a mouse model of rare skeletal dysplasia Acrodysostosis Type 2: cause or consequence of aberrant bone health?, Melissa Bowerman, Keele University, UK

10:55 - 11:20 Exploring the Role of KLF15 in Laminopathies: The Case of LMNA-Associated Congenital Muscular Dystrophy, Ignacio Perez de Castro, National Institute of Health Carlos III (ISCIII)

11:20 - 11:45 TBA

11:45 - 12:10 TBA

12:10 - 13:30 Lunch break

13:30 - 15:10 – Session 6: Gender specific and gastrointestinal tumour diseases

Chairs: Gwen Lomberk, Medical College of Wisconsin, USA / TBA

13:30- 13:55 Targeting KLF5 to treat basal-like breast cancer, Ceshi Chen, Kunming Medical University, China

13:55 - 14:20 The role of KLF5 and its acetylation in the prostate cancer microenvironment, Baotong Zhang, Southern University of Science and Technology, School of Medicine, Shenzhen, Guangdong, China

14:20- 14:45 Talk from Jonathan Katz, University of Pennsylvania, USA

14:45-15:00 Coffee break

15:00–16:40 – Session 7: Vascular Biology

Chairs: TBA

15:00 - 15:25 Talk from Toru Suzuki, University of Leicester, UK

15:25 - 15:50 The Role of KLF4-Mediated RNA Regulation in Aneurysm and Its Molecular Mechanisms, Bin Zheng, Hebei Medical University, China

15:50 - 16:15 KLFs and the Endothelium, Jain Mukesh, Brown University, USA

16:15 – 16:40 Non-Cell-Autonomous Effects of KLF15 in Vascular Cells, Laura Priesmeier, Medical University Center Goettingen, Germany

17:15 - 17:45 Translational Session II

Chairs: TBA

18:00–19:00 Closing Keynote

Chairs: Gwen Lomberk, Mayo Clinic Arizona, USA; Konstantinos Drosatos, University of Cincinnati College of Medicine, USA

Keynote: Haldar Saptarsi, USA

20:00 Closing Dinner & Party

Day 4 MONDAY 16th, November 2026

09:00–10:00 Business meeting / KLF/SP community: Presentation of the KLF Society and the next conference

10:00 –11:15– Session 8: Epigenetics & RNA biology

Chairs: TBA

10:00-10:25 Quantitative and specific assessment of KLF4 epigenetic regulation Raffaele Frazzi, Azienda Unità Sanitaria Locale–IRCCS di Reggio Emilia, Italy

10:25-10:50 Post-transcriptional regulation of cardiac physiology, Federica Accornero, Brown University, USA

10:50-11:15 TBA

11:45 Closing remarks, Conference adjourns, Lunch boxes pick-up and Departure

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